HDHD5 (Haloacid Dehalogenase Like Hydrolase Domain Containing 5)
A pseudogene-derived transcript with limited functional annotation in human biology.
Gene Information Card
| Symbol | HDHD5 |
|---|---|
| Full Name | haloacid dehalogenase like hydrolase domain containing 5 |
| Gene Type | pseudogene |
| Chromosomal Location | 3p21.31 |
| NCBI Gene ID | 100129924 ncbi.nlm.nih.gov/gene/100129924 |
| Ensembl ID | ENSG00000214253 |
| UniProt ID | Not available (pseudogene) |
| OMIM ID | Not available |
| HGNC ID | HGNC:37234 |
| Aliases | MGC26816, dJ1181N3.1 |
Description
HDHD5 (haloacid dehalogenase like hydrolase domain containing 5) is a pseudogene located on chromosome 3p21.31. It is classified as a processed pseudogene derived from the HDHD1 gene. No protein product has been experimentally confirmed, and its biological function, if any, remains unknown. Expression data are limited and likely represent background transcription.
Disease Associations
| Disease category | Pathophysiological mechanism | Genomic evidence |
|---|---|---|
| No disease associations | Not applicable | No evidence in ClinVar, OMIM, or COSMIC |
Expression Profile
Tissue Expression
| Tissue | nTPM | level |
|---|---|---|
| Testis | 0.1 | Very low |
| Brain | 0.0 | Not detected |
| Liver | 0.0 | Not detected |
Cell Line Expression
| Cell Line | nTPM | Notes |
|---|---|---|
| HeLa | 0.0 | Not detected |
| HEK293 | 0.0 | Not detected |
| K562 | 0.0 | Not detected |
Data source：Human Protein Atlas（proteinatlas.org）
Mutations & Variants
Hotspot Mutations
| Variant | Type | Frequency | Functional Description |
|---|---|---|---|
| No reported variants | Not applicable | Not applicable | Not applicable |
Mutation functional classification
Loss of Function (LOF)
Not applicable (pseudogene, no protein product)
Gain of Function (GOF)
Not applicable
Dominant Negative (DN)
Not applicable
View complete mutation data：
Protein Summary
HDHD5 is a pseudogene and does not encode a functional protein. The predicted haloacid dehalogenase-like hydrolase domain is not translated due to disruptions in the coding sequence.
Related Services
Related Products
| Product name | Cat.No. | Species | Gene ID | |
|---|---|---|---|---|
| HDHD5 Knockout HEK293 Cell Line | EDJ-KQ3053 | Human | 27440 | Details Get a Quote |
| HDHD5 Knockout A-549 Cell Line | EDJ-KQ24304 | Human | 27440 | Details Get a Quote |
| HDHD5 Knockout HCT 116 Cell Line | EDJ-KQ24305 | Human | 27440 | Details Get a Quote |
| HDHD5 Knockout HeLa Cell Line | EDJ-KQ24306 | Human | 27440 | Details Get a Quote |
