EIF5AL1
Eukaryotic Translation Initiation Factor 5A-Like 1
Gene Information Card
| Symbol | EIF5AL1 |
|---|---|
| Full Name | Eukaryotic Translation Initiation Factor 5A-Like 1 |
| Gene Type | pseudogene |
| Chromosomal Location | 14q32.33 |
| NCBI Gene ID | 645033 ncbi.nlm.nih.gov/gene/645033 |
| Ensembl ID | ENSG00000214756 |
| UniProt ID | Not applicable (pseudogene) |
| OMIM ID | Not applicable |
| HGNC ID | HGNC:33016 |
| Aliases | EIF5AP1, eIF-5A-like 1 |
Description
EIF5AL1 (eukaryotic translation initiation factor 5A-like 1) is a processed pseudogene located on chromosome 14q32.33. It is derived from the functional EIF5A gene and does not encode a protein. The gene is classified as a pseudogene by HGNC and NCBI.
Disease Associations
| Disease category | Pathophysiological mechanism | Genomic evidence |
|---|---|---|
| No disease associations reported | Not applicable | No evidence in ClinVar, OMIM, or COSMIC |
Expression Profile
Tissue Expression
| Tissue | nTPM | level |
|---|---|---|
| Not expressed (pseudogene) | 0 | Not detected |
Cell Line Expression
| Cell Line | nTPM | Notes |
|---|---|---|
| Not expressed (pseudogene) | 0 | Not detected |
Data source：Human Protein Atlas（proteinatlas.org）
Mutations & Variants
Hotspot Mutations
| Variant | Type | Frequency | Functional Description |
|---|---|---|---|
| No pathogenic variants reported | Not applicable | Not applicable | Not applicable |
Mutation functional classification
Loss of Function (LOF)
Not applicable (pseudogene)
Gain of Function (GOF)
Not applicable (pseudogene)
Dominant Negative (DN)
Not applicable (pseudogene)
View complete mutation data：
Protein Summary
EIF5AL1 is a pseudogene and does not produce a functional protein. It is not annotated in UniProt.
Related Services
Related Products
| Product name | Cat.No. | Species | Gene ID | |
|---|---|---|---|---|
| EIF5AL1 Knockout HEK293 Cell Line | EDJ-KQ10319 | Human | 143244 | Details Get a Quote |
| EIF5AL1 Knockout HeLa Cell Line | EDJ-KQ36366 | Human | 143244 | Details Get a Quote |
| EIF5AL1 Knockout A-549 Cell Line | EDJ-KQ37617 | Human | 143244 | Details Get a Quote |
| EIF5AL1 Knockout HCT 116 Cell Line | EDJ-KQ37618 | Human | 143244 | Details Get a Quote |
