CCDC187
Coiled-Coil Domain Containing 187
Gene Information Card
| Symbol | CCDC187 |
|---|---|
| Full Name | Coiled-Coil Domain Containing 187 |
| Gene Type | Protein coding |
| Chromosomal Location | 17q21.31 |
| NCBI Gene ID | 100130502 ncbi.nlm.nih.gov/gene/100130502 |
| Ensembl ID | ENSG00000267280 |
| UniProt ID | A0A1B0GTV5 |
| OMIM ID | - |
| HGNC ID | 44273 |
| Aliases | MGC16384, FLJ45831 |
Description
CCDC187 (Coiled-Coil Domain Containing 187) is a protein-coding gene located on chromosome 17q21.31. The encoded protein contains a coiled-coil domain, which is often involved in protein-protein interactions and structural roles in the cell. Currently, limited functional characterization is available, and no specific disease associations have been firmly established in major databases.
Disease Associations
| Disease category | Pathophysiological mechanism | Genomic evidence |
|---|
Expression Profile
Tissue Expression
| Tissue | nTPM | level |
|---|
Cell Line Expression
| Cell Line | nTPM | Notes |
|---|
Data source：Human Protein Atlas（proteinatlas.org）
Mutations & Variants
Hotspot Mutations
| Variant | Type | Frequency | Functional Description |
|---|
Mutation functional classification
Loss of Function (LOF)
Gain of Function (GOF)
Dominant Negative (DN)
View complete mutation data：
Protein Summary
The CCDC187 protein is predicted to contain a coiled-coil domain, suggesting a role in mediating protein-protein interactions. No experimental functional data are currently available in UniProt or other curated resources.
Related Services
Related Products
| Product name | Cat.No. | Species | Gene ID | |
|---|---|---|---|---|
| CCDC187 Knockout HEK293 Cell Line | EDJ-KQ12802 | Human | 399693 | Details Get a Quote |
