CCDC182
Coiled-Coil Domain Containing 182
Gene Information Card
| Symbol | CCDC182 |
|---|---|
| Full Name | Coiled-Coil Domain Containing 182 |
| Gene Type | Protein coding |
| Chromosomal Location | 17q21.31 |
| NCBI Gene ID | 100130449 ncbi.nlm.nih.gov/gene/100130449 |
| Ensembl ID | ENSG00000267280 |
| UniProt ID | A0A1B0GTV4 |
| OMIM ID | Not available |
| HGNC ID | HGNC:52468 |
| Aliases | FLJ45831, MGC163247 |
Description
CCDC182 (Coiled-Coil Domain Containing 182) is a protein-coding gene located on chromosome 17q21.31. The encoded protein contains a coiled-coil domain, which is often involved in protein-protein interactions, structural organization, and cellular signaling. Currently, the specific biological function of CCDC182 is not fully characterized, and no disease associations have been established in major databases.
Disease Associations
| Disease category | Pathophysiological mechanism | Genomic evidence |
|---|---|---|
| No disease associations reported | Not applicable | No evidence in OMIM, ClinVar, or COSMIC |
Expression Profile
Tissue Expression
| Tissue | nTPM | level |
|---|---|---|
| Testis | 0.6 | Low |
| Thyroid | 0.3 | Low |
| Adrenal gland | 0.2 | Low |
Cell Line Expression
| Cell Line | nTPM | Notes |
|---|---|---|
| HEK 293 | 0.5 | Low expression |
| K562 | 0.1 | Very low expression |
Data source：Human Protein Atlas（proteinatlas.org）
Mutations & Variants
Hotspot Mutations
| Variant | Type | Frequency | Functional Description |
|---|---|---|---|
| No reported mutations | Not applicable | Not applicable | Not applicable |
Mutation functional classification
Loss of Function (LOF)
No data available
Gain of Function (GOF)
No data available
Dominant Negative (DN)
No data available
View complete mutation data：
Protein Summary
The CCDC182 protein is predicted to contain a coiled-coil domain, suggesting a role in mediating protein-protein interactions. Its precise molecular function and cellular localization remain unknown, and no functional studies have been published.
Related Services
Related Products
| Product name | Cat.No. | Species | Gene ID | |
|---|---|---|---|---|
| CCDC182 Knockout HEK293 Cell Line | EDJ-KQ12797 | Human | 101927581 | Details Get a Quote |
| CCDC182 Knockout HeLa Cell Line | EDJ-KQ60995 | Human | 101927581 | Details Get a Quote |
| CCDC182 Knockout A-549 Cell Line | EDJ-KQ69469 | Human | 101927581 | Details Get a Quote |
| CCDC182 Knockout HCT 116 Cell Line | EDJ-KQ77822 | Human | 101927581 | Details Get a Quote |
