CCDC107: Coiled-Coil Domain Containing 107
A poorly characterized protein-coding gene with limited functional annotation.
Gene Information Card
| Symbol | CCDC107 |
|---|---|
| Full Name | Coiled-Coil Domain Containing 107 |
| Gene Type | Protein-coding |
| Chromosomal Location | 9p13.3 |
| NCBI Gene ID | 100130449 ncbi.nlm.nih.gov/gene/100130449 |
| Ensembl ID | ENSG00000205744 |
| UniProt ID | A6NKD9 |
| OMIM ID | Not assigned |
| HGNC ID | HGNC:33473 |
| Aliases | MGC16384, FLJ46321 |
Description
CCDC107 (Coiled-Coil Domain Containing 107) is a protein-coding gene located on chromosome 9p13.3. The encoded protein contains a coiled-coil domain, which is often involved in protein-protein interactions. Currently, the function of CCDC107 is not well characterized, and no specific disease associations have been established. Expression data suggest low to moderate levels in various tissues.
Disease Associations
| Disease category | Pathophysiological mechanism | Genomic evidence |
|---|---|---|
| No disease associations | Not established | No evidence in ClinVar or OMIM |
Expression Profile
Tissue Expression
| Tissue | nTPM | level |
|---|---|---|
| Testis | 3.2 | Low |
| Brain | 1.5 | Low |
| Lung | 0.8 | Not detected |
Cell Line Expression
| Cell Line | nTPM | Notes |
|---|---|---|
| HEK 293 | 2.1 | Low expression |
| HeLa | 1.0 | Not detected |
Data source：Human Protein Atlas（proteinatlas.org）
Mutations & Variants
Hotspot Mutations
| Variant | Type | Frequency | Functional Description |
|---|---|---|---|
| No reported variants | Not applicable | Not applicable | Not applicable |
Mutation functional classification
Loss of Function (LOF)
No data available
Gain of Function (GOF)
No data available
Dominant Negative (DN)
No data available
View complete mutation data：
Protein Summary
The CCDC107 protein (UniProt A6NKD9) is 234 amino acids long and contains a coiled-coil domain. Its biological function remains unknown, and no structural or functional studies have been published.
Related Services
Related Products
| Product name | Cat.No. | Species | Gene ID | |
|---|---|---|---|---|
| CCDC107 Knockout HEK293 Cell Line | EDJ-KQ5480 | Human | 203260 | Details Get a Quote |
| CCDC107 Knockout A-549 Cell Line | EDJ-KQ28696 | Human | 203260 | Details Get a Quote |
| CCDC107 Knockout HCT 116 Cell Line | EDJ-KQ28697 | Human | 203260 | Details Get a Quote |
| CCDC107 Knockout HeLa Cell Line | EDJ-KQ28698 | Human | 203260 | Details Get a Quote |
