C9orf153
Chromosome 9 Open Reading Frame 153
Gene Information Card
| Symbol | C9orf153 |
|---|---|
| Full Name | chromosome 9 open reading frame 153 |
| Gene Type | protein-coding |
| Chromosomal Location | 9q34.3 |
| NCBI Gene ID | 138255 ncbi.nlm.nih.gov/gene/138255 |
| Ensembl ID | ENSG00000180389 |
| UniProt ID | Q5VUJ9 |
| OMIM ID | 617425 |
| HGNC ID | 28300 |
| Aliases | MGC26717 |
Description
C9orf153 (chromosome 9 open reading frame 153) is a protein-coding gene located on the long arm of chromosome 9 (9q34.3). The gene encodes a protein of unknown function. Limited expression data suggest low to moderate expression in certain tissues. No disease associations have been established as of the current knowledge cutoff.
Disease Associations
| Disease category | Pathophysiological mechanism | Genomic evidence |
|---|---|---|
| No known disease associations | Not applicable | No evidence |
Expression Profile
Tissue Expression
| Tissue | nTPM | level |
|---|---|---|
| Testis | 3.2 | Low |
| Thyroid | 1.5 | Low |
| Prostate | 1.1 | Low |
Cell Line Expression
| Cell Line | nTPM | Notes |
|---|---|---|
| HEK 293 | 0.8 | Low expression |
| HeLa | 0.5 | Low expression |
| K562 | 0.3 | Low expression |
Data source：Human Protein Atlas（proteinatlas.org）
Mutations & Variants
Hotspot Mutations
| Variant | Type | Frequency | Functional Description |
|---|---|---|---|
| No reported pathogenic variants | Not applicable | Not applicable | Not applicable |
Mutation functional classification
Loss of Function (LOF)
No data available
Gain of Function (GOF)
No data available
Dominant Negative (DN)
No data available
View complete mutation data：
Protein Summary
The C9orf153 protein (UniProt Q5VUJ9) is 278 amino acids long. Its molecular function and biological role are not characterized. No conserved domains have been identified.
Related Services
Related Products
| Product name | Cat.No. | Species | Gene ID | |
|---|---|---|---|---|
| C9orf153 Knockout HEK293 Cell Line | EDJ-KQ12644 | Human | 389766 | Details Get a Quote |
| C9orf153 Knockout HeLa Cell Line | EDJ-KQ60104 | Human | 389766 | Details Get a Quote |
| C9orf153 Knockout A-549 Cell Line | EDJ-KQ68566 | Human | 389766 | Details Get a Quote |
| C9orf153 Knockout HCT 116 Cell Line | EDJ-KQ76942 | Human | 389766 | Details Get a Quote |
