C8orf88
Chromosome 8 Open Reading Frame 88
Gene Information Card
| Symbol | C8orf88 |
|---|---|
| Full Name | chromosome 8 open reading frame 88 |
| Gene Type | protein-coding |
| Chromosomal Location | 8q24.3 |
| NCBI Gene ID | 100130449 ncbi.nlm.nih.gov/gene/100130449 |
| Ensembl ID | ENSG00000214756 |
| UniProt ID | A0A1B0GTV5 |
| OMIM ID | Not assigned |
| HGNC ID | HGNC:33737 |
| Aliases | FLJ45831 |
Description
C8orf88 is a protein-coding gene located on chromosome 8 at band q24.3. The gene encodes a protein of unknown function. Limited experimental data are available; expression has been detected in some tissues and cell lines. No disease associations have been established in major curated databases.
Disease Associations
| Disease category | Pathophysiological mechanism | Genomic evidence |
|---|---|---|
| No disease associations | Not applicable | No evidence in ClinVar, OMIM, or COSMIC |
Expression Profile
Tissue Expression
| Tissue | nTPM | level |
|---|---|---|
| Testis | 0.5 | Low |
| Brain | 0.2 | Not detected |
| Liver | 0.1 | Not detected |
Cell Line Expression
| Cell Line | nTPM | Notes |
|---|---|---|
| HEK293 | 0.3 | Low expression |
| HeLa | 0.1 | Not detected |
| K562 | 0.0 | Not detected |
Data source：Human Protein Atlas（proteinatlas.org）
Mutations & Variants
Hotspot Mutations
| Variant | Type | Frequency | Functional Description |
|---|---|---|---|
| No curated mutations | Not applicable | Not applicable | Not applicable |
Mutation functional classification
Loss of Function (LOF)
No data
Gain of Function (GOF)
No data
Dominant Negative (DN)
No data
View complete mutation data：
Protein Summary
The C8orf88 protein is predicted to be 143 amino acids long (UniProt A0A1B0GTV5). No functional domains or motifs have been characterized. The protein's biological role remains unknown.
Related Services
Related Products
| Product name | Cat.No. | Species | Gene ID | |
|---|---|---|---|---|
| C8orf88 Knockout HEK293 Cell Line | EDJ-KQ12639 | Human | 100127983 | Details Get a Quote |
| C8orf88 Knockout A-549 Cell Line | EDJ-KQ41710 | Human | 100127983 | Details Get a Quote |
| C8orf88 Knockout HeLa Cell Line | EDJ-KQ41711 | Human | 100127983 | Details Get a Quote |
| C8orf88 Knockout HCT 116 Cell Line | EDJ-KQ77612 | Human | 100127983 | Details Get a Quote |
Displaying Records 1 To 4 Of 4 Records
