C5orf63
Chromosome 5 Open Reading Frame 63
Gene Information Card
| Symbol | C5orf63 |
|---|---|
| Full Name | Chromosome 5 Open Reading Frame 63 |
| Gene Type | Protein-coding |
| Chromosomal Location | 5q31.3 |
| NCBI Gene ID | 401251 ncbi.nlm.nih.gov/gene/401251 |
| Ensembl ID | ENSG00000164172 |
| UniProt ID | Q6ZQY3 |
| OMIM ID | Not assigned |
| HGNC ID | HGNC:34478 |
| Aliases | MGC16384, FLJ45803 |
Description
C5orf63 is a protein-coding gene located on chromosome 5q31.3. The encoded protein has no well-characterized function, but transcript expression has been detected in various tissues. Limited functional data are available, and no disease associations have been firmly established.
Disease Associations
| Disease category | Pathophysiological mechanism | Genomic evidence |
|---|---|---|
| No confirmed disease associations | Unknown | No evidence in ClinVar or OMIM |
Expression Profile
Tissue Expression
| Tissue | nTPM | level |
|---|---|---|
| Testis | 5.2 | Low |
| Brain | 3.1 | Low |
| Lung | 2.0 | Not detected |
| Liver | 1.5 | Not detected |
Cell Line Expression
| Cell Line | nTPM | Notes |
|---|---|---|
| HEK293 | 4.8 | Low expression |
| HeLa | 3.0 | Low expression |
| K562 | 1.2 | Not detected |
Data source：Human Protein Atlas（proteinatlas.org）
Mutations & Variants
Hotspot Mutations
| Variant | Type | Frequency | Functional Description |
|---|---|---|---|
| No reported pathogenic variants | N/A | N/A | N/A |
Mutation functional classification
Loss of Function (LOF)
No data available
Gain of Function (GOF)
No data available
Dominant Negative (DN)
No data available
View complete mutation data：
Protein Summary
The C5orf63 protein (UniProt Q6ZQY3) is 244 amino acids long with no known domains or functional motifs. Its biological role remains uncharacterized.
Related Services
Related Products
| Product name | Cat.No. | Species | Gene ID | |
|---|---|---|---|---|
| C5orf63 Knockout HEK293 Cell Line | EDJ-KQ11626 | Human | 401207 | Details Get a Quote |
| C5orf63 Knockout A-549 Cell Line | EDJ-KQ39976 | Human | 401207 | Details Get a Quote |
| C5orf63 Knockout HCT 116 Cell Line | EDJ-KQ39977 | Human | 401207 | Details Get a Quote |
| C5orf63 Knockout HeLa Cell Line | EDJ-KQ39978 | Human | 401207 | Details Get a Quote |
