C5orf58
Chromosome 5 Open Reading Frame 58
Gene Information Card
| Symbol | C5orf58 |
|---|---|
| Full Name | Chromosome 5 Open Reading Frame 58 |
| Gene Type | Protein-coding |
| Chromosomal Location | 5q31.3 |
| NCBI Gene ID | 100130502 ncbi.nlm.nih.gov/gene/100130502 |
| Ensembl ID | ENSG00000205562 |
| UniProt ID | Q6ZQY3 |
| OMIM ID | Not available |
| HGNC ID | HGNC:37241 |
| Aliases | MGC16384 |
Description
C5orf58 is a protein-coding gene located on chromosome 5q31.3. The encoded protein has no well-characterized function, and its biological role remains largely unknown. Limited expression data suggest low to moderate transcript levels in certain tissues.
Disease Associations
| Disease category | Pathophysiological mechanism | Genomic evidence |
|---|---|---|
| No curated disease associations | Not applicable | No evidence from ClinVar, OMIM, or COSMIC |
Expression Profile
Tissue Expression
| Tissue | nTPM | level |
|---|---|---|
| Testis | 2.3 | Low |
| Thyroid | 1.1 | Low |
| Lung | 0.8 | Not detected |
Cell Line Expression
| Cell Line | nTPM | Notes |
|---|---|---|
| HEK 293 | 0.5 | Low expression |
| HeLa | 0.3 | Not detected |
| K562 | 0.2 | Not detected |
Data source：Human Protein Atlas（proteinatlas.org）
Mutations & Variants
Hotspot Mutations
| Variant | Type | Frequency | Functional Description |
|---|---|---|---|
| No curated mutations | Not applicable | Not applicable | Not applicable |
Mutation functional classification
Loss of Function (LOF)
No data available
Gain of Function (GOF)
No data available
Dominant Negative (DN)
No data available
View complete mutation data：
Protein Summary
The C5orf58 protein (UniProt Q6ZQY3) is 147 amino acids long with no known domains or functional motifs. Its molecular function and cellular localization are uncharacterized.
Related Services
Related Products
| Product name | Cat.No. | Species | Gene ID | |
|---|---|---|---|---|
| C5orf58 Knockout HEK293 Cell Line | EDJ-KQ9325 | Human | 133874 | Details Get a Quote |
