C5orf34
Chromosome 5 Open Reading Frame 34
Gene Information Card
| Symbol | C5orf34 |
|---|---|
| Full Name | chromosome 5 open reading frame 34 |
| Gene Type | protein-coding |
| Chromosomal Location | 5q35.2 |
| NCBI Gene ID | 375332 ncbi.nlm.nih.gov/gene/375332 |
| Ensembl ID | ENSG00000164171 |
| UniProt ID | Q6ZR37 |
| OMIM ID | - |
| HGNC ID | 34307 |
| Aliases | MGC16384 |
Description
C5orf34 is a protein-coding gene located on chromosome 5q35.2. The encoded protein has no well-characterized function, but transcript expression data suggest potential roles in specific tissues. Limited functional studies are available.
Disease Associations
| Disease category | Pathophysiological mechanism | Genomic evidence |
|---|---|---|
| No curated disease associations | Not established | No evidence in OMIM or ClinVar |
Expression Profile
Tissue Expression
| Tissue | nTPM | level |
|---|---|---|
| Testis | 5.2 | Low |
| Thyroid | 3.1 | Low |
| Prostate | 2.8 | Low |
| Adrenal gland | 2.5 | Low |
| Brain (cerebellum) | 2.0 | Low |
Cell Line Expression
| Cell Line | nTPM | Notes |
|---|---|---|
| HEK 293 | 1.5 | Low expression |
| HeLa | 1.2 | Low expression |
| K562 | 0.8 | Very low expression |
Data source：Human Protein Atlas（proteinatlas.org）
Mutations & Variants
Hotspot Mutations
| Variant | Type | Frequency | Functional Description |
|---|---|---|---|
| No curated mutations | - | - | - |
Mutation functional classification
Loss of Function (LOF)
Not established
Gain of Function (GOF)
Not established
Dominant Negative (DN)
Not established
View complete mutation data：
Protein Summary
The C5orf34 protein (UniProt Q6ZR37) is predicted to be a small, uncharacterized protein. No functional domains or known biological processes have been experimentally validated.
Related Services
Related Products
| Product name | Cat.No. | Species | Gene ID | |
|---|---|---|---|---|
| C5orf34 Knockout HEK293 Cell Line | EDJ-KQ11910 | Human | 375444 | Details Get a Quote |
| C5orf34 Knockout A-549 Cell Line | EDJ-KQ41679 | Human | 375444 | Details Get a Quote |
| C5orf34 Knockout HCT 116 Cell Line | EDJ-KQ41681 | Human | 375444 | Details Get a Quote |
| C5orf34 Knockout HeLa Cell Line | EDJ-KQ41682 | Human | 375444 | Details Get a Quote |
