C3orf80
Chromosome 3 Open Reading Frame 80
Gene Information Card
| Symbol | C3orf80 |
|---|---|
| Full Name | chromosome 3 open reading frame 80 |
| Gene Type | protein-coding |
| Chromosomal Location | 3p21.31 |
| NCBI Gene ID | 100130449 ncbi.nlm.nih.gov/gene/100130449 |
| Ensembl ID | ENSG00000214253 |
| UniProt ID | A6NKD9 |
| OMIM ID | Not available |
| HGNC ID | HGNC:33768 |
| Aliases | MGC16384 |
Description
C3orf80 (chromosome 3 open reading frame 80) is a protein-coding gene located on chromosome 3 at band p21.31. The gene encodes a protein of unknown function. Limited expression data suggest low or tissue-specific expression. No disease associations have been established.
Disease Associations
| Disease category | Pathophysiological mechanism | Genomic evidence |
|---|---|---|
| No known disease associations | Not applicable | No evidence |
Expression Profile
Tissue Expression
| Tissue | nTPM | level |
|---|---|---|
| Testis | 0.5 | Low |
| Brain | 0.2 | Not detected |
| Liver | 0.1 | Not detected |
Cell Line Expression
| Cell Line | nTPM | Notes |
|---|---|---|
| HEK293 | 0.3 | Low expression |
| HeLa | 0.1 | Not detected |
| K562 | 0.0 | Not detected |
Data source：Human Protein Atlas（proteinatlas.org）
Mutations & Variants
Hotspot Mutations
| Variant | Type | Frequency | Functional Description |
|---|---|---|---|
| No reported variants | Not applicable | Not applicable | Not applicable |
Mutation functional classification
Loss of Function (LOF)
Not characterized
Gain of Function (GOF)
Not characterized
Dominant Negative (DN)
Not characterized
View complete mutation data：
Protein Summary
The C3orf80 protein (UniProt A6NKD9) is 110 amino acids in length. Its molecular function and biological role are unknown. No structural or functional domains have been annotated.
Related Services
Related Products
| Product name | Cat.No. | Species | Gene ID | |
|---|---|---|---|---|
| C3orf80 Knockout HEK293 Cell Line | EDJ-KQ10914 | Human | 401097 | Details Get a Quote |
| C3orf80 Knockout A-549 Cell Line | EDJ-KQ39961 | Human | 401097 | Details Get a Quote |
| C3orf80 Knockout HCT 116 Cell Line | EDJ-KQ39963 | Human | 401097 | Details Get a Quote |
| C3orf80 Knockout HeLa Cell Line | EDJ-KQ39964 | Human | 401097 | Details Get a Quote |
