C3orf22
Chromosome 3 Open Reading Frame 22
Gene Information Card
| Symbol | C3orf22 |
|---|---|
| Full Name | chromosome 3 open reading frame 22 |
| Gene Type | protein-coding |
| Chromosomal Location | 3q13.2 |
| NCBI Gene ID | 84971 ncbi.nlm.nih.gov/gene/84971 |
| Ensembl ID | ENSG00000163739 |
| UniProt ID | Q8N6T3 |
| OMIM ID | 617437 |
| HGNC ID | 26779 |
| Aliases | FLJ22662, MGC131891 |
Description
C3orf22 (chromosome 3 open reading frame 22) is a protein-coding gene located on the long arm of chromosome 3 (3q13.2). The encoded protein has no well-characterized function and is not associated with any known disease or pathway. Expression data suggest low to moderate levels in certain tissues, but the biological role remains largely unknown.
Disease Associations
| Disease category | Pathophysiological mechanism | Genomic evidence |
|---|---|---|
| No disease associations | Not established | No evidence |
Expression Profile
Tissue Expression
| Tissue | nTPM | level |
|---|---|---|
| Testis | 2.5 | Low |
| Thyroid | 1.8 | Low |
| Adrenal gland | 1.2 | Low |
| Other tissues | <1.0 | Not detected |
Cell Line Expression
| Cell Line | nTPM | Notes |
|---|---|---|
| HEK293 | 0.5 | Low expression |
| HeLa | 0.3 | Low expression |
| K562 | 0.2 | Low expression |
Data source：Human Protein Atlas（proteinatlas.org）
Mutations & Variants
Hotspot Mutations
| Variant | Type | Frequency | Functional Description |
|---|---|---|---|
| No reported variants | N/A | N/A | N/A |
Mutation functional classification
Loss of Function (LOF)
No data
Gain of Function (GOF)
No data
Dominant Negative (DN)
No data
View complete mutation data：
Protein Summary
The C3orf22 protein (UniProt Q8N6T3) is a 244-amino acid polypeptide with no known domains or functional motifs. Its molecular function and cellular role remain uncharacterized.
Related Services
Related Products
| Product name | Cat.No. | Species | Gene ID | |
|---|---|---|---|---|
| C3orf22 Knockout HEK293 Cell Line | EDJ-KQ11374 | Human | 152065 | Details Get a Quote |
| C3orf22 Knockout HeLa Cell Line | EDJ-KQ58700 | Human | 152065 | Details Get a Quote |
| C3orf22 Knockout A-549 Cell Line | EDJ-KQ67184 | Human | 152065 | Details Get a Quote |
| C3orf22 Knockout HCT 116 Cell Line | EDJ-KQ75587 | Human | 152065 | Details Get a Quote |
