C20orf141
Chromosome 20 Open Reading Frame 141
Gene Information Card
| Symbol | C20orf141 |
|---|---|
| Full Name | chromosome 20 open reading frame 141 |
| Gene Type | protein-coding |
| Chromosomal Location | 20q13.33 |
| NCBI Gene ID | 285600 ncbi.nlm.nih.gov/gene/285600 |
| Ensembl ID | ENSG00000196476 |
| UniProt ID | Q5VY43 |
| OMIM ID | 618218 |
| HGNC ID | 16129 |
| Aliases | MGC26717 |
Description
C20orf141 is a protein-coding gene located on chromosome 20q13.33. The encoded protein has no well-characterized function but is predicted to be involved in cellular processes based on sequence homology. Limited expression data suggest low to moderate transcript levels in certain tissues.
Disease Associations
| Disease category | Pathophysiological mechanism | Genomic evidence |
|---|---|---|
| No known disease associations | Not applicable | No evidence in ClinVar, OMIM, or COSMIC |
Expression Profile
Tissue Expression
| Tissue | nTPM | level |
|---|---|---|
| Testis | 2.1 | Low |
| Brain | 0.8 | Not detected |
| Liver | 0.5 | Not detected |
Cell Line Expression
| Cell Line | nTPM | Notes |
|---|---|---|
| HEK293 | 1.5 | Low expression |
| HeLa | 0.9 | Not detected |
Data source：Human Protein Atlas（proteinatlas.org）
Mutations & Variants
Hotspot Mutations
| Variant | Type | Frequency | Functional Description |
|---|---|---|---|
| No reported pathogenic variants | Not applicable | Not applicable | Not applicable |
Mutation functional classification
Loss of Function (LOF)
Not established
Gain of Function (GOF)
Not established
Dominant Negative (DN)
Not established
View complete mutation data：
Protein Summary
The C20orf141 protein (UniProt Q5VY43) is 141 amino acids long with no known functional domains. Its biological role remains uncharacterized.
Related Services
Related Products
| Product name | Cat.No. | Species | Gene ID | |
|---|---|---|---|---|
| C20orf141 Knockout HEK293 Cell Line | EDJ-KQ9192 | Human | 128653 | Details Get a Quote |
| C20orf141 Knockout HeLa Cell Line | EDJ-KQ58246 | Human | 128653 | Details Get a Quote |
| C20orf141 Knockout A-549 Cell Line | EDJ-KQ66734 | Human | 128653 | Details Get a Quote |
| C20orf141 Knockout HCT 116 Cell Line | EDJ-KQ75145 | Human | 128653 | Details Get a Quote |
