BRD3OS
BRD3 Opposite Strand (Non-Protein Coding)
Gene Information Card
| Symbol | BRD3OS |
|---|---|
| Full Name | BRD3 Opposite Strand (Non-Protein Coding) |
| Gene Type | lncRNA (long non-coding RNA) |
| Chromosomal Location | 9q34.2 |
| NCBI Gene ID | 100130449 ncbi.nlm.nih.gov/gene/100130449 |
| Ensembl ID | ENSG00000267280 |
| UniProt ID | N/A (non-protein coding) |
| OMIM ID | Not assigned |
| HGNC ID | HGNC:40010 |
| Aliases | BRD3-AS, BRD3 antisense RNA 1 |
Description
BRD3OS (BRD3 Opposite Strand) is a long non-coding RNA (lncRNA) gene located on chromosome 9q34.2. It is transcribed from the opposite strand of the BRD3 gene and is classified as a non-protein coding RNA. Its biological function is not fully characterized, but lncRNAs often regulate gene expression through chromatin remodeling, transcriptional interference, or post-transcriptional mechanisms. BRD3OS may play a role in cellular processes and has been implicated in certain cancers, though detailed functional studies are limited.
Disease Associations
| Disease category | Pathophysiological mechanism | Genomic evidence |
|---|---|---|
| Cancer (general) | Potential dysregulation of BRD3OS expression may contribute to oncogenic pathways, possibly through interaction with BRD3 or other chromatin regulators. | Limited; expression changes observed in tumor samples (COSMIC) |
Expression Profile
Tissue Expression
| Tissue | nTPM | level |
|---|---|---|
| Testis | 0.0 | Not detected |
| Brain | 0.0 | Not detected |
| Lung | 0.0 | Not detected |
| Breast | 0.0 | Not detected |
| Colon | 0.0 | Not detected |
Cell Line Expression
| Cell Line | nTPM | Notes |
|---|---|---|
| HEK293 | 0.0 | Not detected |
| HeLa | 0.0 | Not detected |
| K562 | 0.0 | Not detected |
Data source：Human Protein Atlas（proteinatlas.org）
Mutations & Variants
Hotspot Mutations
| Variant | Type | Frequency | Functional Description |
|---|---|---|---|
| No curated mutations | N/A | N/A | N/A |
Mutation functional classification
Loss of Function (LOF)
Not applicable; no protein product.
Gain of Function (GOF)
Not applicable; no protein product.
Dominant Negative (DN)
Not applicable; no protein product.
View complete mutation data：
Protein Summary
BRD3OS does not encode a protein. It is a long non-coding RNA gene. Therefore, no protein product is produced.
Related Services
Related Products
| Product name | Cat.No. | Species | Gene ID | |
|---|---|---|---|---|
| BRD3OS Knockout HEK293 Cell Line | EDJ-KQ12565 | Human | 266655 | Details Get a Quote |
| BRD3OS Knockout A-549 Cell Line | EDJ-KQ41582 | Human | 266655 | Details Get a Quote |
| BRD3OS Knockout HCT 116 Cell Line | EDJ-KQ41583 | Human | 266655 | Details Get a Quote |
| BRD3OS Knockout HeLa Cell Line | EDJ-KQ41584 | Human | 266655 | Details Get a Quote |
