ANKRD9 Gene - Ankyrin Repeat Domain 9
Comprehensive guide to ANKRD9: genomic location, expression, function, and clinical significance.
Gene Information Card
| Symbol | ANKRD9 |
|---|---|
| Full Name | ankyrin repeat domain 9 |
| Gene Type | gene with protein product |
| Chromosomal Location | 14q32.31 |
| NCBI Gene ID | 122416 ncbi.nlm.nih.gov/gene/122416 |
| Ensembl ID | ENSG00000156381 |
| UniProt ID | Q96BM1 |
| OMIM ID | 618605 |
| HGNC ID | HGNC:20096 |
| Aliases | Not available |
Description
ANKRD9 (ankyrin repeat domain 9) is a protein-coding gene located on chromosome 14q32.31. It encodes a protein containing ankyrin repeats, which are known to mediate protein-protein interactions. The exact function of ANKRD9 is not fully characterized, but it is expressed in various tissues and may play a role in cellular signaling or structural organization. Mutations in ANKRD9 have been associated with certain diseases, and its expression is altered in some cancers.
Disease Associations
| Disease category | Pathophysiological mechanism | Genomic evidence |
|---|---|---|
| Not specified | Not specified | No disease association has been reported in major databases. |
Expression Profile
Tissue Expression
| Tissue | nTPM | level |
|---|---|---|
| Testis | Not available | Not available |
| Kidney | Not available | Not available |
| Liver | Not available | Not available |
Cell Line Expression
| Cell Line | nTPM | Notes |
|---|---|---|
| Not specified | Not available | No cell line expression data available. |
Data source：Human Protein Atlas（proteinatlas.org）
Mutations & Variants
Hotspot Mutations
| Variant | Type | Frequency | Functional Description |
|---|---|---|---|
| Not specified | Not specified | Not specified | No mutations have been reported in major databases. |
Mutation functional classification
Loss of Function (LOF)
No data available.
Gain of Function (GOF)
No data available.
Dominant Negative (DN)
No data available.
View complete mutation data：
Gene Ontology (GO)
| • Molecular function: Not available | • Biological process: Not available |
| • Cellular component: Not available |
Protein Summary
The ANKRD9 protein contains ankyrin repeats, which are common protein-protein interaction motifs. It is predicted to be involved in cellular processes such as signal transduction or cytoskeletal organization. However, detailed functional studies are lacking, and the protein's exact role remains to be elucidated.
Related Services
Related Products
| Product name | Cat.No. | Species | Gene ID | |
|---|---|---|---|---|
| ANKRD9 Knockout HEK293 Cell Line | EDJ-KQ8150 | Human | 122416 | Details Get a Quote |
| ANKRD9 Knockout A-549 Cell Line | EDJ-KQ34053 | Human | 122416 | Details Get a Quote |
| ANKRD9 Knockout HCT 116 Cell Line | EDJ-KQ34054 | Human | 122416 | Details Get a Quote |
| ANKRD9 Knockout HeLa Cell Line | EDJ-KQ34055 | Human | 122416 | Details Get a Quote |
