ANKRD61
Ankyrin Repeat Domain 61
Gene Information Card
| Symbol | ANKRD61 |
|---|---|
| Full Name | Ankyrin Repeat Domain 61 |
| Gene Type | protein-coding |
| Chromosomal Location | 5q35.3 |
| NCBI Gene ID | 100131211 ncbi.nlm.nih.gov/gene/100131211 |
| Ensembl ID | ENSG00000204983 |
| UniProt ID | A6NKD9 |
| OMIM ID | - |
| HGNC ID | 37293 |
| Aliases | MGC16384 |
Description
ANKRD61 (Ankyrin Repeat Domain 61) is a protein-coding gene located on chromosome 5q35.3. The encoded protein contains ankyrin repeat domains, which are typically involved in protein-protein interactions. Currently, limited functional characterization is available, and no specific disease associations have been firmly established in major databases.
Disease Associations
| Disease category | Pathophysiological mechanism | Genomic evidence |
|---|---|---|
| - | - | - |
Expression Profile
Tissue Expression
| Tissue | nTPM | level |
|---|---|---|
| Testis | 0.8 | Low |
| Brain | 0.5 | Low |
| Lung | 0.3 | Low |
Cell Line Expression
| Cell Line | nTPM | Notes |
|---|---|---|
| HEK293 | 0.2 | Low expression |
| K562 | 0.1 | Low expression |
Data source：Human Protein Atlas（proteinatlas.org）
Mutations & Variants
Hotspot Mutations
| Variant | Type | Frequency | Functional Description |
|---|---|---|---|
| - | - | - | - |
Mutation functional classification
Loss of Function (LOF)
Not characterized
Gain of Function (GOF)
Not characterized
Dominant Negative (DN)
Not characterized
View complete mutation data：
Protein Summary
The ANKRD61 protein contains ankyrin repeat domains, which are common motifs mediating protein-protein interactions. Its specific biological function remains poorly understood, and no structural or functional data are available in UniProt.
Related Services
Related Products
| Product name | Cat.No. | Species | Gene ID | |
|---|---|---|---|---|
| ANKRD61 Knockout HEK293 Cell Line | EDJ-KQ12375 | Human | 100310846 | Details Get a Quote |
| ANKRD61 Knockout A-549 Cell Line | EDJ-KQ41241 | Human | 100310846 | Details Get a Quote |
| ANKRD61 Knockout HCT 116 Cell Line | EDJ-KQ41242 | Human | 100310846 | Details Get a Quote |
| ANKRD61 Knockout HeLa Cell Line | EDJ-KQ41243 | Human | 100310846 | Details Get a Quote |
Displaying Records 1 To 4 Of 4 Records
