Overview
Experimental Controls
Study and implement experimental control strategies for CRISPR experiments, including non-targeting controls, safe harbor integrations and normalization methods.
What is Experimental Controls ?
Experimental controls are essential for attributing observed phenotypic changes specifically to the intended genetic perturbation. They include non-targeting sgRNA controls, wild-type reference lines, safe harbor knockins and rescue experiments. Rigorous controls rule out clonal variation, Cas9 toxicity and off-target effects, ensuring CRISPR data validity and reproducibility.
Key Research Applications
Non-targeting sgRNA control cell line generation
Safe harbor (AAVS1/ROSA26) integration validation
CRISPR-induced off-target site sequencing
Rescue (cDNA add-back) experiment design
Batch effect and clonal variability assessment
Products
Featured/Popular Targets
ALL
HPRT1
B2M
G6PD
TFRC
| Product name | Cat.No. | Species | Gene ID | |
|---|---|---|---|---|
| B2M Knockout A-549 Cell Line | EDC07863 | Human | 567 | Details Get a Quote |
| B2M Knockout HEK293T Cell Line | EDC07693 | Human | 567 | Details Get a Quote |
| B2M Knockout Hep-G2 Cell Line | EDJ-KQ38 | Human | 567 | Details Get a Quote |
| B2M Knockout C2C12 Cell Line | EDJ-KQ82 | Mouse | 12010 | Details Get a Quote |
| B2M Knockout K-562 Cell Line | EDJ-KQ85 | Human | 567 | Details Get a Quote |
| B2M Knockout SNU-449 Cell Line | EDJ-KQ89 | Human | 567 | Details Get a Quote |
| B2M Knockout THP-1 Cell Line | EDJ-KQ91 | Human | 567 | Details Get a Quote |
| TFRC Knockout HEK293 Cell Line | EDC08077 | Human | 7037 | Details Get a Quote |
| HPRT1 Knockout HEK293 Cell Line | EDJ-KQ3913 | Human | 3251 | Details Get a Quote |
| B2M Knockout HEK293 Cell Line | EDJ-KQ12503 | Human | 567 | Details Get a Quote |
| HPRT1 Knockout A-549 Cell Line | EDJ-KQ26134 | Human | 3251 | Details Get a Quote |
| HPRT1 Knockout HCT 116 Cell Line | EDJ-KQ26135 | Human | 3251 | Details Get a Quote |
| HPRT1 Knockout HeLa Cell Line | EDC90498 | Human | 3251 | Details Get a Quote |
| B2M Knockout HCT 116 Cell Line | EDJ-KQ41482 | Human | 567 | Details Get a Quote |
| B2M Knockout HeLa Cell Line | EDJ-KQ41483 | Human | 567 | Details Get a Quote |
Displaying Records 1 To 15 Of 35 Records
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