pLentiCRISPR v2-CYP8B1-Puro-OE
EDITGENE guarantees pLentiCRISPR v2-CYP8B1-Puro-OE plasmid has passed QC, endotoxin-free, and project validated. more
Cat.No: EDV196
Quantity
EDITGENE guarantees pLentiCRISPR v2-CYP8B1-Puro-OE plasmid has passed QC, endotoxin-free, and project validated.
| Plasmid Resistance | Amp |
|---|---|
| E.coli | stbl3 |
| Type | OE |
| Selection Marker | Puro |
| Tag | 3xFLAG |
| Gene | CYP8B1 |
| Gene ID | |
| Gene Synonyms | CP8B|CYP12|CYPVIIIB1 |
| Summary |
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the conversion of 7 alpha-hydroxy-4-cholesten-3-one into 7-alpha,12-alpha-dihydroxy-4-cholesten-3-one. The balance between these two steroids determines the relative amounts of cholic acid and chenodeoxycholic acid both of which are secreted in the bile and affect the solubility of cholesterol. This gene is unique among the cytochrome P450 genes in that it is intronless. [provided by RefSeq, Jul 2008]
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* For research use only. Not intended for use in humans or animals, including clinical, therapeutic, or diagnostic purposes.
Storage
Store at -20 ºC for short term. -91 ºC for long term preservation.
* Research Use Disclaimer: Content is generated from publicly available research data, bioinformatic resources, and computational analyses for research reference only.
