pLentiCRISPR v2-CYP7A1-Puro-OE
EDITGENE guarantees pLentiCRISPR v2-CYP7A1-Puro-OE plasmid has passed QC, endotoxin-free, and project validated. more
Cat.No: EDV195
Quantity
EDITGENE guarantees pLentiCRISPR v2-CYP7A1-Puro-OE plasmid has passed QC, endotoxin-free, and project validated.
| Plasmid Resistance | Amp |
|---|---|
| E.coli | stbl3 |
| Type | OE |
| Selection Marker | Puro |
| Tag | 3xFLAG |
| Gene | CYP7A1 |
| Gene ID | |
| Gene Synonyms | CP7A|CYP7|CYPVII |
| Summary |
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the first reaction in the cholesterol catabolic pathway in the liver, which converts cholesterol to bile acids. This reaction is the rate limiting step and the major site of regulation of bile acid synthesis, which is the primary mechanism for the removal of cholesterol from the body. Polymorphisms in the promoter of this gene are associated with defects in bile acid synthesis. [provided by RefSeq, Feb 2010]
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* For research use only. Not intended for use in humans or animals, including clinical, therapeutic, or diagnostic purposes.
Storage
Store at -20 ºC for short term. -90 ºC for long term preservation.
* Research Use Disclaimer: Content is generated from publicly available research data, bioinformatic resources, and computational analyses for research reference only.
