pLentiCRISPR v2-CYP19A1-Puro-OE
EDITGENE guarantees pLentiCRISPR v2-CYP19A1-Puro-OE plasmid has passed QC, endotoxin-free, and project validated. more
Cat.No: EDV194
Quantity
EDITGENE guarantees pLentiCRISPR v2-CYP19A1-Puro-OE plasmid has passed QC, endotoxin-free, and project validated.
| Plasmid Resistance | Amp |
|---|---|
| E.coli | stbl3 |
| Type | OE |
| Selection Marker | Puro |
| Tag | 3xFLAG |
| Gene | CYP19A1 |
| Gene ID | |
| Gene Synonyms | ARO|ARO1|CPV1|CYAR|CYP19|CYPXIX|P-450AROM |
| Summary |
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and catalyzes the last steps of estrogen biosynthesis. Mutations in this gene can result in either increased or decreased aromatase activity; the associated phenotypes suggest that estrogen functions both as a sex steroid hormone and in growth or differentiation. Alternative promoter use and alternative splicing results in multiple transcript variants that have different tissue specificities. [provided by RefSeq, Dec 2016]
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* For research use only. Not intended for use in humans or animals, including clinical, therapeutic, or diagnostic purposes.
Storage
Store at -20 ºC for short term. -89 ºC for long term preservation.
* Research Use Disclaimer: Content is generated from publicly available research data, bioinformatic resources, and computational analyses for research reference only.
