pLentiCRISPR v2-CYP17A1-Puro-OE
EDITGENE guarantees pLentiCRISPR v2-CYP17A1-Puro-OE plasmid has passed QC, endotoxin-free, and project validated. more
Cat.No: EDV193
Quantity
EDITGENE guarantees pLentiCRISPR v2-CYP17A1-Puro-OE plasmid has passed QC, endotoxin-free, and project validated.
| Plasmid Resistance | Amp |
|---|---|
| E.coli | stbl3 |
| Type | OE |
| Selection Marker | Puro |
| Tag | 3xFLAG |
| Gene | CYP17A1 |
| Gene ID | |
| Gene Synonyms | CPT7|CYP17|P450C17|S17AH |
| Summary |
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. It has both 17alpha-hydroxylase and 17,20-lyase activities and is a key enzyme in the steroidogenic pathway that produces progestins, mineralocorticoids, glucocorticoids, androgens, and estrogens. Mutations in this gene are associated with isolated steroid-17 alpha-hydroxylase deficiency, 17-alpha-hydroxylase/17,20-lyase deficiency, pseudohermaphroditism, and adrenal hyperplasia. [provided by RefSeq, Jul 2008]
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* For research use only. Not intended for use in humans or animals, including clinical, therapeutic, or diagnostic purposes.
Storage
Store at -20 ºC for short term. -88 ºC for long term preservation.
* Research Use Disclaimer: Content is generated from publicly available research data, bioinformatic resources, and computational analyses for research reference only.
