Sqstm1 Knockout RAW 264.7 Cell Line
Cat.No.:
EDJ-KZ493
Species:
Mouse
Cell Name:
RAW 264.7
Gene:
Sqstm1
Gene ID:
18412
Size:
1×10⁶cells
| Cat.No. | EDJ-KZ493 |
|---|---|
| Product Name | Sqstm1 Knockout RAW 264.7 Cell Line |
| Cell Line | RAW 264.7 |
| Cellosaurus ID | CVCL_0493 |
| Cell Line Synonyms | RAW264, RAW2647, RAW264.7, RAW-264.7, Raw 264.7, Raw264.7 |
| Gene | Sqstm1 |
| NCBI Gene ID | |
| Gene Synonyms | A170|DMRV|EBIAP|FTDALS3|NADGP|OSIL|PDB3|ZIP3|p60|p62|p62B |
| Associated Diseases | Leukemia |
| QC | Indels validated by Sanger sequencing; sterility confirmed via microbial testing. |
* For research use only. Not intended for use in humans or animals, including clinical, therapeutic, or diagnostic purposes.
| Loci | STR Info (Sample Cell) Sample Cell Line: RAW 264.7 | STR Info (Cell bank) Cell Line: RAW 264.7 | ||
| Allele1 | Allele2 | Allele1 | Allele2 | |
| 1-1 | 16 | 15 | 16 | |
| 1-2 | 17 | 17 | ||
| 2-1 | 16 | 16 | ||
| 3-2 | 14 | 14 | ||
| 4-2 | 22.3 | 22.3 | ||
| 5-5 | 14 | 15 | 14 | |
| 6-4 | 17 | 18 | 18 | |
| 6-7 | 12 | 13 | 12 | |
| 7-1 | 25.2 | 25.2 | ||
| 8-1 | 13 | 13 | ||
| 11-2 | 17 | 17 | ||
| 12-1 | 16 | 16 | ||
| 13-1 | 16.2 | 16.2 | ||
| 15-3 | 22.3 | 22.3 | ||
| 17-2 | 14 | 16 | 14 | 16 |
| 18-3 | 18 | 18 | ||
| 19-2 | 14 | 14 | ||
| X-1 | 24 | 24 | ||
* STR authentication data of this cell line matches with that of cell lines sourced from ATCC, DSMZ, JCRB, and RIKEN databases.
Conclusion: The STR identification of this cell is correct.
Conclusion: The STR identification of this cell is correct.
* Research Use Disclaimer: Content is generated from publicly available research data, bioinformatic resources, and computational analyses for research reference only.
Related Publications
TYROBP modulates NFκB phosphorylation and SQSTM1 expression in macrophages during Brucella Abortus LPS infection.
IF=1.8
Research in veterinary science
This KO model may be useful for:
- Investigating the role of SQSTM1 in macrophage innate immune signaling, particularly NFκB pathway modulation.
- Studying host-pathogen interactions, including responses to *Brucella abortus* LPS infection.
- Elucidating the functional interplay between TYROBP and SQSTM1 in inflammatory signaling cascades.
- Evaluating SQSTM1-dependent regulation of autophagy and its crosstalk with immune receptor signaling.
- Serving as a cellular tool for screening anti-inflammatory or anti-infective compounds targeting SQSTM1-mediated pathways.
Required Accessories
Cell Culture Optimization Series
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