LentiCRISPR v2-BMP15-sgRNA1-GFP
EDITGENE guarantees LentiCRISPR v2-BMP15-sgRNA1-GFP plasmid has passed QC, endotoxin-free, and project validated. more
Cat.No: EDV256
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EDITGENE guarantees LentiCRISPR v2-BMP15-sgRNA1-GFP plasmid has passed QC, endotoxin-free, and project validated.
| Plasmid Resistance | Amp |
|---|---|
| Type | KO |
| Selection Marker | / |
| Tag | / |
| Gene ID | |
| Gene | [{"genemapName":"BMP15","genemapSta":1}] |
| Gene Synonyms | GDF9B|ODG2|POF4 |
| Summary |
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate subunits of a disulfide-linked homodimer, or alternatively, a heterodimer, with the related protein, growth differentiation factor 9 (GDF9). This protein plays a role in oocyte maturation and follicular development, through activation of granulosa cells. Defects in this gene are the cause of ovarian dysgenesis and are associated with premature ovarian failure. [provided by RefSeq, Aug 2016]
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* For research use only. Not intended for use in humans or animals, including clinical, therapeutic, or diagnostic purposes.
Storage
Store at -20 ºC for short term. -80 ºC for long term preservation.
* Research Use Disclaimer: Content is generated from publicly available research data, bioinformatic resources, and computational analyses for research reference only.
