XNDC1N Gene - XRCC1 N-terminal Domain Containing 1, N-terminal Like
Comprehensive genomic and proteomic information for XNDC1N (HGNC:54661) at 11q13.4.
Gene Information Card
| Symbol | XNDC1N |
|---|---|
| Full Name | XRCC1 N-terminal domain containing 1, N-terminal like |
| Gene Type | gene with protein product |
| Chromosomal Location | 11q13.4 |
| NCBI Gene ID | 100133315 ncbi.nlm.nih.gov/gene/100133315 |
| Ensembl ID | ENSG00000254469 |
| UniProt ID | Q6ZNB5 |
| OMIM ID | Not available |
| HGNC ID | HGNC:54661 |
| Aliases | Not available |
Description
XNDC1N (XRCC1 N-terminal domain containing 1, N-terminal like) is a protein-coding gene located on chromosome 11q13.4. The gene is also known by its Entrez ID 100133315 and Ensembl ID ENSG00000254469. The protein product is annotated in UniProt as Q6ZNB5. As of the latest data, no OMIM entry is available, and no aliases have been reported. The gene is classified as a gene with protein product, but its specific biological functions and clinical significance are still under investigation.
Disease Associations
| Disease category | Pathophysiological mechanism | Genomic evidence |
|---|---|---|
| Not established | No disease association has been reported for XNDC1N. | No evidence from ClinVar or OMIM. |
Expression Profile
Tissue Expression
| Tissue | nTPM | level |
|---|---|---|
| Not available | Not available | No expression data available. |
Cell Line Expression
| Cell Line | nTPM | Notes |
|---|---|---|
| Not available | Not available | No cell line expression data available. |
Data source：Human Protein Atlas（proteinatlas.org）
Mutations & Variants
Hotspot Mutations
| Variant | Type | Frequency | Functional Description |
|---|---|---|---|
| Not available | Not available | Not available | Not available |
Mutation functional classification
Loss of Function (LOF)
No data available.
Gain of Function (GOF)
No data available.
Dominant Negative (DN)
No data available.
View complete mutation data：
Protein Summary
The XNDC1N gene encodes a protein with an N-terminal domain similar to that of XRCC1, a protein involved in DNA repair. However, the exact function of the XNDC1N protein is not yet characterized. The protein sequence is available under UniProt ID Q6ZNB5, but no functional domains or interactions have been experimentally validated. Further research is needed to elucidate its role in cellular processes.
Related Services
Related Products
| Product name | Cat.No. | Species | Gene ID | |
|---|---|---|---|---|
| XNDC1N Knockout HEK293 Cell Line | EDJ-KQ16161 | Human | 100133315 | Details Get a Quote |
| XNDC1N Knockout A-549 Cell Line | EDJ-KQ46123 | Human | 100133315 | Details Get a Quote |
| XNDC1N Knockout HCT 116 Cell Line | EDJ-KQ47352 | Human | 100133315 | Details Get a Quote |
| XNDC1N Knockout HeLa Cell Line | EDJ-KQ47353 | Human | 100133315 | Details Get a Quote |
Displaying Records 1 To 4 Of 4 Records
