UQCRHL
Ubiquinol-Cytochrome c Reductase Hinge Protein Like
Gene Information Card
| Symbol | UQCRHL |
|---|---|
| Full Name | Ubiquinol-Cytochrome c Reductase Hinge Protein Like |
| Gene Type | Protein coding |
| Chromosomal Location | 1p36.33 |
| NCBI Gene ID | 100130449 ncbi.nlm.nih.gov/gene/100130449 |
| Ensembl ID | ENSG00000229807 |
| UniProt ID | A0A1B0GTV4 |
| OMIM ID | - |
| HGNC ID | 37289 |
| Aliases | UQCRH-like, MGC16384 |
Description
UQCRHL (Ubiquinol-Cytochrome c Reductase Hinge Protein Like) is a protein-coding gene located on chromosome 1p36.33. It is predicted to be involved in mitochondrial electron transport, specifically as a component of complex III (cytochrome bc1 complex), based on sequence similarity to UQCRH. The gene encodes a small hinge protein that may facilitate electron transfer between cytochrome c1 and cytochrome c.
Disease Associations
| Disease category | Pathophysiological mechanism | Genomic evidence |
|---|---|---|
| No curated disease associations | Not established | No evidence |
Expression Profile
Tissue Expression
| Tissue | nTPM | level |
|---|---|---|
| Testis | 0.0 | Not detected |
| Brain | 0.0 | Not detected |
| Heart | 0.0 | Not detected |
| Liver | 0.0 | Not detected |
Cell Line Expression
| Cell Line | nTPM | Notes |
|---|---|---|
| No data available | N/A | N/A |
Data source：Human Protein Atlas（proteinatlas.org）
Mutations & Variants
Hotspot Mutations
| Variant | Type | Frequency | Functional Description |
|---|---|---|---|
| No curated mutations | N/A | N/A | N/A |
Mutation functional classification
Loss of Function (LOF)
No data
Gain of Function (GOF)
No data
Dominant Negative (DN)
No data
View complete mutation data：
Protein Summary
The UQCRHL protein is a putative component of mitochondrial complex III, involved in the electron transport chain. Its exact function remains to be fully characterized, but it is thought to play a role in the transfer of electrons from ubiquinol to cytochrome c.
Related Services
Related Products
| Product name | Cat.No. | Species | Gene ID | |
|---|---|---|---|---|
| UQCRHL Knockout HEK293 Cell Line | EDJ-KQ16044 | Human | 440567 | Details Get a Quote |
| UQCRHL Knockout A-549 Cell Line | EDJ-KQ47164 | Human | 440567 | Details Get a Quote |
| UQCRHL Knockout HCT 116 Cell Line | EDJ-KQ47165 | Human | 440567 | Details Get a Quote |
| UQCRHL Knockout HeLa Cell Line | EDJ-KQ47166 | Human | 440567 | Details Get a Quote |
Displaying Records 1 To 4 Of 4 Records
