TRIM39-RPP21 Gene
Readthrough transcript encoding TRIM39 and RPP21 proteins
Gene Information Card
| Symbol | TRIM39-RPP21 |
|---|---|
| Full Name | TRIM39-RPP21 readthrough (NMD candidate) |
| Gene Type | Readthrough transcript (protein-coding) |
| Chromosomal Location | 6p22.1 |
| NCBI Gene ID | 100526839 ncbi.nlm.nih.gov/gene/100526839 |
| Ensembl ID | ENSG00000269313 |
| UniProt ID | Not available (readthrough product not independently curated) |
| OMIM ID | Not available |
| HGNC ID | HGNC:37211 |
| Aliases | TRIM39-RPP21 readthrough, TRIM39-RPP21 fusion |
Description
TRIM39-RPP21 is a readthrough transcript located on chromosome 6p22.1 that spans the adjacent TRIM39 and RPP21 genes. The transcript is predicted to undergo nonsense-mediated decay (NMD) and may not produce a stable protein product. It is listed in NCBI Gene and HGNC as a readthrough candidate.
Disease Associations
| Disease category | Pathophysiological mechanism | Genomic evidence |
|---|---|---|
| No specific disease association | Not established | No evidence in ClinVar or OMIM |
Expression Profile
Tissue Expression
| Tissue | nTPM | level |
|---|---|---|
| No tissue expression data available | N/A | N/A |
Cell Line Expression
| Cell Line | nTPM | Notes |
|---|---|---|
| No cell line expression data available | N/A | N/A |
Data source：Human Protein Atlas（proteinatlas.org）
Mutations & Variants
Hotspot Mutations
| Variant | Type | Frequency | Functional Description |
|---|---|---|---|
| No curated mutations | N/A | N/A | N/A |
Mutation functional classification
Loss of Function (LOF)
Not applicable
Gain of Function (GOF)
Not applicable
Dominant Negative (DN)
Not applicable
View complete mutation data：
Protein Summary
The TRIM39-RPP21 readthrough transcript is predicted to be a candidate for nonsense-mediated decay, and no stable protein product has been characterized. The individual TRIM39 and RPP21 proteins are encoded by separate genes; TRIM39 is involved in ubiquitination and immune regulation, while RPP21 is a component of RNase P/MRP complexes.
Related Services
Related Products
| Product name | Cat.No. | Species | Gene ID | |
|---|---|---|---|---|
| TRIM39-RPP21 Knockout HEK293 Cell Line | EDJ-KQ52138 | Human | 202658 | Details Get a Quote |
| TRIM39-RPP21 Knockout HeLa Cell Line | EDJ-KQ59036 | Human | 202658 | Details Get a Quote |
| TRIM39-RPP21 Knockout A-549 Cell Line | EDJ-KQ67515 | Human | 202658 | Details Get a Quote |
| TRIM39-RPP21 Knockout HCT 116 Cell Line | EDJ-KQ75913 | Human | 202658 | Details Get a Quote |
Displaying Records 1 To 4 Of 4 Records
