TEKTIP1
Tektin-like Protein 1
Gene Information Card
| Symbol | TEKTIP1 |
|---|---|
| Full Name | tektin-like protein 1 |
| Gene Type | protein-coding |
| Chromosomal Location | 1p36.33 |
| NCBI Gene ID | 100505746 ncbi.nlm.nih.gov/gene/100505746 |
| Ensembl ID | ENSG00000284823 |
| UniProt ID | A0A1B0GTV4 |
| OMIM ID | 620129 |
| HGNC ID | 53830 |
| Aliases | C1orf233, TEKTIP1 |
Description
TEKTIP1 (tektin-like protein 1) is a protein-coding gene located on chromosome 1p36.33. The encoded protein is predicted to be involved in microtubule-associated processes, though its specific biological function remains under investigation. Expression data suggest low to moderate levels in select tissues.
Disease Associations
| Disease category | Pathophysiological mechanism | Genomic evidence |
|---|---|---|
| No disease associations currently curated | Not established | No evidence in ClinVar or OMIM |
Expression Profile
Tissue Expression
| Tissue | nTPM | level |
|---|---|---|
| Testis | 2.1 | Low |
| Brain | 1.0 | Low |
| Lung | 0.5 | Not detected |
Cell Line Expression
| Cell Line | nTPM | Notes |
|---|---|---|
| HEK293 | 0.8 | Low expression |
| K562 | 0.3 | Not detected |
Data source：Human Protein Atlas（proteinatlas.org）
Mutations & Variants
Hotspot Mutations
| Variant | Type | Frequency | Functional Description |
|---|---|---|---|
| No pathogenic variants reported | N/A | N/A | N/A |
Mutation functional classification
Loss of Function (LOF)
No data available
Gain of Function (GOF)
No data available
Dominant Negative (DN)
No data available
View complete mutation data：
Protein Summary
TEKTIP1 encodes a small protein of unknown function, predicted to localize to the cytoplasm. No structural or functional domains have been experimentally validated.
Related Services
Related Products
| Product name | Cat.No. | Species | Gene ID | |
|---|---|---|---|---|
| TEKTIP1 Knockout HEK293 Cell Line | EDJ-KQ14898 | Human | 100128569 | Details Get a Quote |
| TEKTIP1 Knockout A-549 Cell Line | EDJ-KQ46584 | Human | 100128569 | Details Get a Quote |
| TEKTIP1 Knockout HCT 116 Cell Line | EDJ-KQ46586 | Human | 100128569 | Details Get a Quote |
| TEKTIP1 Knockout HeLa Cell Line | EDJ-KQ46587 | Human | 100128569 | Details Get a Quote |
Displaying Records 1 To 4 Of 4 Records
