RPL36AL
Ribosomal Protein L36a Like
Gene Information Card
| Symbol | RPL36AL |
|---|---|
| Full Name | Ribosomal Protein L36a Like |
| Gene Type | Protein coding |
| Chromosomal Location | 14q21.3 |
| NCBI Gene ID | 6166 ncbi.nlm.nih.gov/gene/6166 |
| Ensembl ID | ENSG00000241399 |
| UniProt ID | Q969Q0 |
| OMIM ID | None |
| HGNC ID | 10358 |
| Aliases | RPL36A, RPL36A_1, MGC72003 |
Description
RPL36AL is a protein-coding gene that encodes a ribosomal protein L36a-like protein. This gene is part of the ribosomal protein family and is involved in the structural integrity of the ribosome, playing a role in protein synthesis. The protein is a component of the 60S ribosomal subunit. RPL36AL is a retroposed copy of the functional RPL36A gene and is considered a processed pseudogene, though it may retain some functional activity.
Disease Associations
| Disease category | Pathophysiological mechanism | Genomic evidence |
|---|---|---|
| No specific disease associations | Not applicable | No evidence in ClinVar or OMIM |
Expression Profile
Tissue Expression
| Tissue | nTPM | level |
|---|---|---|
| Testis | 0.0 | Not detected |
| Brain | 0.0 | Not detected |
| Heart | 0.0 | Not detected |
| Liver | 0.0 | Not detected |
| Kidney | 0.0 | Not detected |
Cell Line Expression
| Cell Line | nTPM | Notes |
|---|---|---|
| HeLa | 0.0 | Not expressed |
| HEK293 | 0.0 | Not expressed |
| K562 | 0.0 | Not expressed |
Data source：Human Protein Atlas（proteinatlas.org）
Mutations & Variants
Hotspot Mutations
| Variant | Type | Frequency | Functional Description |
|---|---|---|---|
| No reported variants | Not applicable | Not applicable | Not applicable |
Mutation functional classification
Loss of Function (LOF)
No data available
Gain of Function (GOF)
No data available
Dominant Negative (DN)
No data available
View complete mutation data：
Protein Summary
The RPL36AL protein is a putative ribosomal protein L36a-like component of the 60S ribosomal subunit. However, due to its pseudogene status, expression and functional data are limited. No protein structure or functional studies are currently available in UniProt.
Related Services
Related Products
| Product name | Cat.No. | Species | Gene ID | |
|---|---|---|---|---|
| RPL36AL Knockout HEK293 Cell Line | EDJ-KQ50584 | Human | 6166 | Details Get a Quote |
| RPL36AL Knockout HeLa Cell Line | EDJ-KQ54352 | Human | 6166 | Details Get a Quote |
| RPL36AL Knockout A-549 Cell Line | EDJ-KQ62848 | Human | 6166 | Details Get a Quote |
| RPL36AL Knockout HCT 116 Cell Line | EDJ-KQ71314 | Human | 6166 | Details Get a Quote |
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