RPL17-C18orf32 readthrough (NMD candidate)
A readthrough transcript between ribosomal protein L17 and C18orf32, likely subject to nonsense-mediated decay.
Gene Information Card
| Symbol | RPL17-C18orf32 |
|---|---|
| Full Name | RPL17-C18orf32 readthrough (NMD candidate) |
| Gene Type | readthrough transcript (NMD candidate) |
| Chromosomal Location | 18q21.1 |
| NCBI Gene ID | 100526820 ncbi.nlm.nih.gov/gene/100526820 |
| Ensembl ID | ENSG00000267508 |
| UniProt ID | Not applicable (NMD candidate) |
| OMIM ID | Not available |
| HGNC ID | HGNC:44591 |
| Aliases | RPL17-C18orf32 readthrough |
Description
RPL17-C18orf32 is a readthrough transcript that spans the genomic region between the RPL17 (ribosomal protein L17) and C18orf32 genes on chromosome 18q21.1. This transcript is predicted to be a candidate for nonsense-mediated decay (NMD), meaning it is unlikely to produce a stable protein product. The readthrough event may represent a transcriptional or processing artifact, and no functional protein has been characterized.
Disease Associations
| Disease category | Pathophysiological mechanism | Genomic evidence |
|---|---|---|
| No disease associations | Not applicable | No evidence in ClinVar, OMIM, or COSMIC |
Expression Profile
Tissue Expression
| Tissue | nTPM | level |
|---|---|---|
| Not available | Not available | Not available |
Cell Line Expression
| Cell Line | nTPM | Notes |
|---|---|---|
| Not available | Not available | Not available |
Data source：Human Protein Atlas（proteinatlas.org）
Mutations & Variants
Hotspot Mutations
| Variant | Type | Frequency | Functional Description |
|---|---|---|---|
| Not available | Not available | Not available | Not available |
Mutation functional classification
Loss of Function (LOF)
Not applicable; NMD candidate transcript.
Gain of Function (GOF)
Not applicable; NMD candidate transcript.
Dominant Negative (DN)
Not applicable; NMD candidate transcript.
View complete mutation data：
Protein Summary
RPL17-C18orf32 is a readthrough transcript that is predicted to undergo nonsense-mediated decay. No protein product has been experimentally confirmed, and it is not expected to encode a functional protein.
Related Services
Related Products
| Product name | Cat.No. | Species | Gene ID | |
|---|---|---|---|---|
| RPL17-C18orf32 Knockout HEK293 Cell Line | EDJ-KQ52480 | Human | 100526842 | Details Get a Quote |
| RPL17-C18orf32 Knockout HeLa Cell Line | EDJ-KQ60943 | Human | 100526842 | Details Get a Quote |
| RPL17-C18orf32 Knockout A-549 Cell Line | EDJ-KQ69418 | Human | 100526842 | Details Get a Quote |
| RPL17-C18orf32 Knockout HCT 116 Cell Line | EDJ-KQ77769 | Human | 100526842 | Details Get a Quote |
Displaying Records 1 To 4 Of 4 Records
