MARCOL Gene: Function, Expression, and Clinical Significance
Comprehensive resource for MARCOL (MARCO like) gene, including genomic context, expression, and potential implications.
Gene Information Card
| Symbol | MARCOL |
|---|---|
| Full Name | MARCO like |
| Gene Type | gene with protein product |
| Chromosomal Location | 5q32 |
| NCBI Gene ID | 105378220 ncbi.nlm.nih.gov/gene/105378220 |
| Ensembl ID | ENSG00000248109 |
| UniProt ID | A0A1B0GUY1 |
| OMIM ID | Not available |
| HGNC ID | HGNC:53644 |
| Aliases | Not available |
Description
MARCOL (MARCO like) is a protein-coding gene located on chromosome 5q32. It is a relatively uncharacterized gene, with limited information available regarding its function and clinical significance. The gene is predicted to encode a protein, but its exact role in cellular processes remains to be fully elucidated. MARCOL may share structural or functional similarities with MARCO (Macrophage Receptor with Collagenous structure), a scavenger receptor involved in immune response, but further research is needed to confirm any functional relationship.
Disease Associations
| Disease category | Pathophysiological mechanism | Genomic evidence |
|---|---|---|
| Disease | Mechanism | Evidence |
Expression Profile
Tissue Expression
| Tissue | nTPM | level |
|---|---|---|
| Tissue | nTPM | Level |
Cell Line Expression
| Cell Line | nTPM | Notes |
|---|---|---|
| Cell Line | nTPM | Notes |
Data source：Human Protein Atlas（proteinatlas.org）
Mutations & Variants
Hotspot Mutations
| Variant | Type | Frequency | Functional Description |
|---|---|---|---|
| Variant | Type | Frequency | Effect |
Mutation functional classification
Loss of Function (LOF)
No data available
Gain of Function (GOF)
No data available
Dominant Negative (DN)
No data available
View complete mutation data：
Protein Summary
The MARCOL gene encodes a protein with the UniProt ID A0A1B0GUY1. The protein sequence is predicted to be 213 amino acids long, but its function is not yet characterized. Based on its similarity to MARCO, it may be involved in immune response or pathogen recognition, but experimental validation is required. No functional domains or motifs have been annotated.
Related Services
Related Products
| Product name | Cat.No. | Species | Gene ID | |
|---|---|---|---|---|
| MARCOL Knockout HEK293 Cell Line | EDJ-KQ14204 | Human | 105378220 | Details Get a Quote |
| MARCOL Knockout HeLa Cell Line | EDJ-KQ44154 | Human | 105378220 | Details Get a Quote |
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