CEBPZOS: CEBPZ Opposite Strand Antisense RNA
A long non-coding RNA with potential roles in transcriptional regulation and cancer.
Gene Information Card
| Symbol | CEBPZOS |
|---|---|
| Full Name | CEBPZ Opposite Strand Antisense RNA |
| Gene Type | lncRNA (long non-coding RNA) |
| Chromosomal Location | 2p22.2 |
| NCBI Gene ID | 101928152 ncbi.nlm.nih.gov/gene/101928152 |
| Ensembl ID | ENSG00000237235 |
| UniProt ID | N/A (non-coding RNA) |
| OMIM ID | N/A |
| HGNC ID | HGNC:40091 |
| Aliases | C2orf76-AS1, LINC00299 |
Description
CEBPZOS (CEBPZ Opposite Strand Antisense RNA) is a long non-coding RNA (lncRNA) gene located on chromosome 2p22.2. It is transcribed from the opposite strand of the CEBPZ gene, which encodes a transcription factor. The function of CEBPZOS is not fully characterized, but lncRNAs often regulate gene expression through various mechanisms, including chromatin remodeling, transcriptional interference, and post-transcriptional regulation. Preliminary studies suggest CEBPZOS may be dysregulated in certain cancers, though its specific role remains under investigation.
Disease Associations
| Disease category | Pathophysiological mechanism | Genomic evidence |
|---|---|---|
| Cancer (general) | Potential dysregulation; lncRNAs can act as oncogenes or tumor suppressors | Limited; expression changes observed in some cancer transcriptome studies |
Expression Profile
Tissue Expression
| Tissue | nTPM | level |
|---|---|---|
| Testis | 0.3 | Low |
| Brain | 0.1 | Low |
| Lung | 0.1 | Low |
| Liver | 0.1 | Low |
Cell Line Expression
| Cell Line | nTPM | Notes |
|---|---|---|
| K562 (leukemia) | 0.2 | Low expression |
| HeLa (cervical) | 0.1 | Low expression |
| HepG2 (liver) | 0.1 | Low expression |
Data source：Human Protein Atlas（proteinatlas.org）
Mutations & Variants
Hotspot Mutations
| Variant | Type | Frequency | Functional Description |
|---|---|---|---|
| No specific mutations reported | N/A | N/A | N/A |
Mutation functional classification
Loss of Function (LOF)
Not established; no functional studies available.
Gain of Function (GOF)
Not established; no functional studies available.
Dominant Negative (DN)
Not applicable; lncRNA.
View complete mutation data：
Protein Summary
CEBPZOS does not encode a protein; it functions as a long non-coding RNA.
Related Services
Related Products
| Product name | Cat.No. | Species | Gene ID | |
|---|---|---|---|---|
| CEBPZOS Knockout HEK293 Cell Line | EDJ-KQ12854 | Human | 100505876 | Details Get a Quote |
| CEBPZOS Knockout A-549 Cell Line | EDJ-KQ42014 | Human | 100505876 | Details Get a Quote |
| CEBPZOS Knockout HCT 116 Cell Line | EDJ-KQ42015 | Human | 100505876 | Details Get a Quote |
| CEBPZOS Knockout HeLa Cell Line | EDJ-KQ42016 | Human | 100505876 | Details Get a Quote |
Displaying Records 1 To 4 Of 4 Records
