CCDC200 Gene - Coiled-Coil Domain Containing 200
Comprehensive guide to CCDC200: genomic location, expression, and clinical significance.
Gene Information Card
| Symbol | CCDC200 |
|---|---|
| Full Name | coiled-coil domain containing 200 |
| Gene Type | gene with protein product |
| Chromosomal Location | 17q21.31 |
| NCBI Gene ID | 100874261 ncbi.nlm.nih.gov/gene/100874261 |
| Ensembl ID | ENSG00000236383 |
| UniProt ID | A0A1B0GVQ3 |
| OMIM ID | Not available |
| HGNC ID | HGNC:43658 |
| Aliases | TMEM106A-AS1, LINC00854 |
Description
CCDC200 (coiled-coil domain containing 200) is a protein-coding gene located on chromosome 17q21.31. It is also known as TMEM106A-AS1 and LINC00854. The gene is characterized by the presence of coiled-coil domains, which are structural motifs involved in protein-protein interactions. Although its full functional significance is not yet fully understood, CCDC200 is expressed in various tissues and may play a role in cellular processes. This article provides a comprehensive overview of CCDC200, including its genomic context, expression patterns, and potential implications in disease.
Disease Associations
| Disease category | Pathophysiological mechanism | Genomic evidence |
|---|---|---|
| Not established | No direct disease association reported | No evidence |
Expression Profile
Tissue Expression
| Tissue | nTPM | level |
|---|---|---|
| Testis | Not available | Not available |
| Brain | Not available | Not available |
| Lung | Not available | Not available |
Cell Line Expression
| Cell Line | nTPM | Notes |
|---|---|---|
| Not available | Not available | No data |
Data source：Human Protein Atlas（proteinatlas.org）
Mutations & Variants
Hotspot Mutations
| Variant | Type | Frequency | Functional Description |
|---|---|---|---|
| Not available | Not available | Not available | Not available |
Mutation functional classification
Loss of Function (LOF)
No data available
Gain of Function (GOF)
No data available
Dominant Negative (DN)
No data available
View complete mutation data：
Protein Summary
The CCDC200 protein is predicted to contain coiled-coil domains, which are common in proteins involved in structural roles and protein-protein interactions. However, the specific function of CCDC200 remains largely uncharacterized. Further research is needed to elucidate its biological roles and potential implications in human health.
Related Services
Related Products
| Product name | Cat.No. | Species | Gene ID | |
|---|---|---|---|---|
| CCDC200 Knockout HEK293 Cell Line | EDJ-KQ12810 | Human | 100874261 | Details Get a Quote |
| CCDC200 Knockout HeLa Cell Line | EDJ-KQ41943 | Human | 100874261 | Details Get a Quote |
| CCDC200 Knockout HCT 116 Cell Line | EDJ-KQ40694 | Human | 100874261 | Details Get a Quote |
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