C14orf39
Chromosome 14 Open Reading Frame 39
Gene Information Card
| Symbol | C14orf39 |
|---|---|
| Full Name | Chromosome 14 Open Reading Frame 39 |
| Gene Type | Protein-coding |
| Chromosomal Location | 14q24.3 |
| NCBI Gene ID | 317749 ncbi.nlm.nih.gov/gene/317749 |
| Ensembl ID | ENSG00000100823 |
| UniProt ID | Q8N6T3 |
| OMIM ID | 617307 |
| HGNC ID | 28235 |
| Aliases | FLJ32743, MGC35130 |
Description
C14orf39 is a protein-coding gene located on chromosome 14q24.3. Its function is not fully characterized, but it is predicted to be involved in cellular processes. Expression data suggest low to moderate levels in various tissues.
Disease Associations
| Disease category | Pathophysiological mechanism | Genomic evidence |
|---|---|---|
| No specific disease association | Unknown | No evidence in ClinVar or OMIM |
Expression Profile
Tissue Expression
| Tissue | nTPM | level |
|---|---|---|
| Testis | 2.3 | Low |
| Brain | 1.1 | Low |
| Lung | 0.8 | Not detected |
| Liver | 0.5 | Not detected |
Cell Line Expression
| Cell Line | nTPM | Notes |
|---|---|---|
| HEK293 | 1.5 | Low expression |
| HeLa | 0.9 | Not detected |
| K562 | 0.6 | Not detected |
Data source：Human Protein Atlas（proteinatlas.org）
Mutations & Variants
Hotspot Mutations
| Variant | Type | Frequency | Functional Description |
|---|---|---|---|
| No reported variants | N/A | N/A | N/A |
Mutation functional classification
Loss of Function (LOF)
No data
Gain of Function (GOF)
No data
Dominant Negative (DN)
No data
View complete mutation data：
Protein Summary
The C14orf39 protein is encoded by the C14orf39 gene. Its molecular function and biological role remain largely unknown, with no characterized domains or motifs.
Related Services
Related Products
| Product name | Cat.No. | Species | Gene ID | |
|---|---|---|---|---|
| C14orf39 Knockout HEK293 Cell Line | EDJ-KQ8909 | Human | 317761 | Details Get a Quote |
| C14orf39 Knockout HeLa Cell Line | EDJ-KQ59572 | Human | 317761 | Details Get a Quote |
| C14orf39 Knockout A-549 Cell Line | EDJ-KQ68037 | Human | 317761 | Details Get a Quote |
| C14orf39 Knockout HCT 116 Cell Line | EDJ-KQ76417 | Human | 317761 | Details Get a Quote |
Displaying Records 1 To 4 Of 4 Records
