Overview
Energy Metabolism & Mitochondria
Study oxidative phosphorylation, TCA cycle, mitochondrial dynamics and bioenergetic regulation using CRISPR-engineered cell models.
What is Energy Metabolism & Mitochondria ?
Energy metabolism centers on the conversion of nutrients into ATP through glycolysis, the tricarboxylic acid (TCA) cycle and oxidative phosphorylation (OXPHOS) in mitochondria. Mitochondrial function also encompasses fusion/fission dynamics, calcium handling and apoptosis. Metabolic reprogramming is a hallmark of cancer and relevant to obesity, diabetes and neurodegeneration.
Key Research Applications
Seahorse respirometry (OCR/ECAR) profiling
Mitochondrial membrane potential (TMRE/JC-1) assays
TCA cycle metabolomics with 13C-labeled substrates
Mitochondrial DNA copy number and gene editing
PGC-1α/PPARγ coactivator pathway studies
Products
Featured/Popular Targets
ALL
NDUFS4
SDHB
ATP5IF1
SLC25A3
SLC25A4
SLC25A5
SLC25A6
SLC25A1
SLC25A10
SLC25A11
SLC25A12
SLC25A13
SLC25A14
SLC25A15
SLC25A16
SLC25A17
SLC25A18
SLC25A19
SLC25A20
SLC25A21
SLC25A22
SLC25A23
SLC25A24
SLC25A25
SLC25A26
SLC25A27
SLC25A28
SLC25A29
SLC25A30
SLC25A32
SLC25A33
SLC25A34
SLC25A35
SLC25A36
SLC25A37
SLC25A38
SLC25A39
SLC25A40
SLC25A42
SLC25A43
SLC25A44
SLC25A45
SLC25A46
SLC25A51
TOMM70
PINK1
PARK7
BNIP3
BNIP3L
PRKAA1
PRKAA2
VDAC1
| Product name | Cat.No. | Species | Gene ID | |
|---|---|---|---|---|
| SLC25A5 Knockout HEK293T Cell Line | EDJ-KQ01 | Human | 292 | Details Get a Quote |
| PARK7 Knockout HT22 Cell Line | EDJ-KQ72 | Mouse | 57320 | Details Get a Quote |
| PRKAA1 Knockout HEK293 Cell Line | EDJ-KQ860 | Human | 5562 | Details Get a Quote |
| PRKAA2 Knockout HEK293 Cell Line | EDJ-KQ861 | Human | 5563 | Details Get a Quote |
| PARK7 Knockout HEK293 Cell Line | EDJ-KQ969 | Human | 11315 | Details Get a Quote |
| BNIP3 Knockout HEK293 Cell Line | EDJ-KQ1023 | Human | 664 | Details Get a Quote |
| SLC25A4 Knockout HEK293 Cell Line | EDJ-KQ1627 | Human | 291 | Details Get a Quote |
| SLC25A6 Knockout HEK293 Cell Line | EDJ-KQ1628 | Human | 293 | Details Get a Quote |
| SLC25A21 Knockout HEK293 Cell Line | EDJ-KQ1981 | Human | 89874 | Details Get a Quote |
| SLC25A29 Knockout HEK293 Cell Line | EDJ-KQ2594 | Human | 123096 | Details Get a Quote |
| SLC25A13 Knockout HEK293 Cell Line | EDJ-KQ2598 | Human | 10165 | Details Get a Quote |
| SLC25A42 Knockout HEK293 Cell Line | EDJ-KQ2661 | Human | 284439 | Details Get a Quote |
| PINK1 Knockout HEK293 Cell Line | EDJ-KQ3426 | Human | 65018 | Details Get a Quote |
| NDUFS4 Knockout HEK293 Cell Line | EDJ-KQ3451 | Human | 4724 | Details Get a Quote |
| SLC25A39 Knockout HEK293 Cell Line | EDJ-KQ3773 | Human | 51629 | Details Get a Quote |
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