ANKRD36B Gene - Ankyrin Repeat Domain 36B
Comprehensive genomic and functional analysis of ANKRD36B
Gene Information Card
| Symbol | ANKRD36B |
|---|---|
| Full Name | Ankyrin Repeat Domain 36B |
| Gene Type | Protein coding |
| Chromosomal Location | 2q11.2 |
| NCBI Gene ID | 84750 ncbi.nlm.nih.gov/gene/84750 |
| Ensembl ID | ENSG00000162961 |
| UniProt ID | Q8N6N3 |
| OMIM ID | 615933 |
| HGNC ID | 26779 |
| Aliases | ANKRD36, FLJ14431, MGC16121 |
Description
ANKRD36B (ankyrin repeat domain 36B) is a protein-coding gene located on chromosome 2q11.2. It encodes a protein containing ankyrin repeats, which are involved in protein-protein interactions. The gene is part of a family of ankyrin repeat domain genes, and its specific function remains under investigation, though it may play roles in cellular signaling and structural organization.
Disease Associations
| Disease category | Pathophysiological mechanism | Genomic evidence |
|---|---|---|
| No curated disease associations | Not established | No evidence in ClinVar or OMIM |
Expression Profile
Tissue Expression
| Tissue | nTPM | level |
|---|---|---|
| Testis | 2.1 | Low |
| Brain | 1.5 | Low |
| Heart | 0.8 | Not detected |
Cell Line Expression
| Cell Line | nTPM | Notes |
|---|---|---|
| HEK293 | 0.5 | Low expression |
| K562 | 0.3 | Low expression |
| HeLa | 0.2 | Not detected |
Data source：Human Protein Atlas（proteinatlas.org）
Mutations & Variants
Hotspot Mutations
| Variant | Type | Frequency | Functional Description |
|---|---|---|---|
| No curated variants | N/A | N/A | N/A |
Mutation functional classification
Loss of Function (LOF)
No data available
Gain of Function (GOF)
No data available
Dominant Negative (DN)
No data available
View complete mutation data：
Protein Summary
The ANKRD36B protein contains ankyrin repeat domains, which are common motifs mediating protein-protein interactions. Its precise biological function is not fully characterized, but it may be involved in cytoskeletal organization or signal transduction.
Related Services
Related Products
| Product name | Cat.No. | Species | Gene ID | |
|---|---|---|---|---|
| ANKRD36B Knockout HEK293 Cell Line | EDJ-KQ12367 | Human | 57730 | Details Get a Quote |
| ANKRD36B Knockout A-549 Cell Line | EDJ-KQ41219 | Human | 57730 | Details Get a Quote |
| ANKRD36B Knockout HCT 116 Cell Line | EDJ-KQ41220 | Human | 57730 | Details Get a Quote |
| ANKRD36B Knockout HeLa Cell Line | EDJ-KQ41221 | Human | 57730 | Details Get a Quote |
Displaying Records 1 To 4 Of 4 Records
